Economic implications of nesiritide versus dobutamine in the treatment of patients with acutely decompensated congestive heart failure.
نویسندگان
چکیده
Pooled data from trials comparing nesiritide with dobutamine for treatment of acute decompensated congestive heart failure were combined with national hospital cost data in an economic model. Results indicate that the acquisition cost of nesiritide is fully offset by decreased hospital costs.
منابع مشابه
Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failure.
OBJECTIVES This study was designed to determine whether nesiritide, administered for acute decompensated congestive heart failure (CHF), affects healthcare costs by hospital length of stay (LOS), readmissions and short-term mortality, compared to dobutamine. BACKGROUND Dobutamine is a commonly used inotropic treatment for CHF. Although dobutamine may have favorable hemodynamic and symptomatic...
متن کاملComparison of the occurrence of ventricular arrhythmias in patients with acutely decompensated congestive heart failure receiving dobutamine versus nesiritide therapy.
Ventricular arrhythmias are common in patients with congestive heart failure (CHF) and may be exacerbated by positive inotropic therapy. Because human B-type natriuretic peptide (nesiritide), an arterial and venodilator, inhibits sympathetic activity, it may decrease the incidence of arrhythmias. Our investigation compares the arrhythmogenicity of dobutamine with nesiritide. A total of 305 pati...
متن کاملIntravenous Nesiritide vs Nitroglycerin for Treatment of Decompensated Congestive Heart Failure A Randomized Controlled Trial
HEART FAILURE OCCURS IN 4.7 million persons living in the United States, and is the discharge diagnosis in approximately 3.5 million hospitalizations annually. Hospitalizations account for 60% of health care expenditures for heart failure. Despite its enormous human and economic burden, no new intravenous agents for acutely decompensated congestive heart fa i lure (CHF) have been approved for u...
متن کاملEffect of nesiritide (B-type natriuretic peptide) and dobutamine on ventricular arrhythmias in the treatment of patients with acutely decompensated congestive heart failure: the PRECEDENT study.
BACKGROUND Dobutamine is commonly used as a means of treating decompensated congestive heart failure (CHF). Although typically effective at improving short-term hemodynamics and symptomatology, the frequent occurrence of arrhythmias and tachycardia is undesirable. In this randomized, multicenter trial, we compared the safety and clinical effectiveness of the cardiac hormone nesiritide (human B-...
متن کاملShort-term risk of death after treatment with nesiritide for decompensated heart failure: a pooled analysis of randomized controlled trials.
CONTEXT Nesiritide improves symptoms in patients with acutely decompensated heart failure compared with placebo and appears to be safer than dobutamine. Its short-term safety relative to standard diuretic and vasodilator therapies is less clear. OBJECTIVE To investigate the safety of nesiritide relative to noninotrope-based control therapies, primarily consisting of diuretics or vasodilators....
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عنوان ژورنال:
- The American journal of cardiology
دوره 92 5 شماره
صفحات -
تاریخ انتشار 2003